Year: 2017
Type: article
Abstract: Authors have conducted analyses of current scientific domestic and foreign data on pathogenesis of congenital malformations of maxillofacial region in human. Perspective of scientific research on face abnormalities causes and complications have been also determined. Literature review showed topic relevance and importance of its further study that aims to improve scientific basis for better methods of prevention, early diagnostic and effective surgical correction of face malformations. The newest morphological data will help to reduce the proportion of face congenital malformations in the structure of infant mortality and disability. It is also noted that severe anatomical, functional and cosmetic defects in maxillofacial area lead to secondary complications development. Review article provides information on current classifications of congenital face malformations, possible ways its pathogenesis, clinical manifestations and methods of surgical correction; possible combined face malformations syndromes and examples of such prenatal diagnosed cases. Anyways, discussions on pathogenetical mecha-nism of certain rare face malformations still remain (craniofacial syndromes, frontonasal dysplasia etc.). The usage of complex modern morphological modeling methods to study features of normal human morphogenesis in dynamics of prenatal development will contribute to a better understanding of face congenital defects pathogenesis, improvement of existing and developing new methods of prevention, diagnosis and surgical treatment.
Source: Bukovinian Medical Herald
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2897682178