Work

Posterior reversible encephalopathy syndrome during treatment with tocilizumab in juvenile idiopathic arthritis

Year: 2018

Type: article

Abstract: A 17-year-old man with normal blood pressure presented with acute bilateral blindness, and retro-orbital pain two days after treatment with tocilizumab (TCZ) for juvenile idiopathic arthritis.The diagnosis was posterior reversible encephalopathy syndrome (PRES), made after clinical examination and MRI (Figure ).Tocilizumab was discontinued and the patient partially improved.To the best of our knowledge, there are no reports of this association (PRES and TCZ) in PubMed.This manuscript describes a new association between TCZ and PRES based on imaging findings, in which the patient presented with more severe imaging findings and did not have complete recovery of the symptoms 1,2,3 .

Source: Arquivos de Neuro-Psiquiatria

DOI: 10.1590/0004-282x20180093

Authors: Marcos Rosa Júnior, Érico Induzzi Borges, Ana Paula Alves Fonseca, Juliana Largura Fiorot, Lídia Balarini, Valéria Valim

Institution: Universidade Federal do Espírito Santo

Language: English

Topic: Neurological Complications and Syndromes

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $200