Work

Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ1) receptor selective ligands

Year: 2018

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2018.12.048

Authors: Rajendra Uprety, András Váradi, Abdullah Allaoa, Gabriel N. Redel-Traub, Travis C. Palmer, Evan N. Feinberg, Alex C. Ferris, Vijay S. Pande, Gavril W. Pasternak, Susruta Majumdar

Institutions: Memorial Sloan Kettering Cancer Center, Stanford University, University of Health Sciences and Pharmacy, Washington University in St. Louis

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Cancer Institute, National Institute of General Medical Sciences

Awards: G1287527835, Opioidergic alkaloids from Mitragynia Speciosa (kratom) as novel treatment for alcohol use disorder, G24590609, Pharmacological Probes based on mitragynine pseudoindoxyl, Pharmacological Probes based on mitragynine pseudoindoxyl, Molecular Biophysics Training Program at Stanford, Pharmacology of opioid actions in vivo, G5117853546, Chemistry and Biology of Mitragynine Alkaloids, Synthesis and pharmacology of novel opiates and their modulatory systems, PHARMACOLOGY OF OPIOID RECEPTOR SUBTYPES, G7183986547, Analgesics targeting truncated 6transmembrane exon 11 variants of MOR-1 (6TM-E11), G9000203847, Cancer Center Support Grant, Behavioral Pharmacology of Human Drug Use Disorders

OpenAlex ID: W2906251908

FWCI: 0.512

Cites: 56

Cited by: 8

Related to: 10