Multidrug Resistant Uropathogens in Urinary Tract Infections and Their Antibiotic Susceptibility Patterns
Year: 2018
Type: article
Study design: Observational Study
Abstract: Objectives: To determine the frequency of multidrug resistant uropathogens and their antibiotic susceptibility patterns.Material and Methods: This study was conducted in Medical B unit at Khyber Teaching Hospital, Peshawar, Pakistanfrom January 2015 to December 2015. A total of 539 cultures were processed and conventional microbiological techniqueswere used to isolate MDR and non MDR uropathogens. Antibiotic sensitivities were determined through KirbyBauer disc diffusion methods. Data was analyzed through SPSS version 20.Results: Out of 539 samples cultured, 375 grew significant growth. Mean age was 41.9 ± 18.9SD. UTI was more commonin females (68.3% n=256) than males 31.7% (n=119). E. Coli was the most common organism isolated (78.1%).Out of 375 isolates, 221 (58.9%) were multidrug resistant. MDR strains were highly sensitive to imipenem (95.1%),meropenem (95%), tazobactum/piperacillin (92.9%), cefoperazonesulbactum (91.1%) and amikacin (90.1%) and leastsensitive to ampicillin (2.8%) and nalidixic acid (3.5%).Conclusion: Multidrug resistance in UTI is becoming a major health problem. Assessment of the risk factors, surveillanceof resistance patterns and policies for proper antimicrobial use are urgently warranted.
Source: Journal of Medical Sciences
Authors: Muhammad Shabbir, Noor Ul Iman, Muhammad Zahir Shah
Institution: Khyber Teaching Hospital
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2907613798