Large-Scale Analysis of Flavobacterium psychrophilum Multilocus Sequence Typing Genotypes Recovered from North American Salmonids Indicates that both Newly Identified and Recurrent Clonal Complexes Are Associated with Disease
Year: 2019
Type: article
Abstract: Flavobacterium psychrophilum is the causative agent of bacterial coldwater disease (BCWD) and rainbow trout fry syndrome (RTFS), both of which cause substantial losses in farmed fish populations worldwide. To better prevent and control BCWD and RTFS outbreaks, we sought to characterize the genetic diversity of several hundred F. psychrophilum isolates that were recovered from diseased fish across North America. Results highlighted multiple F. psychrophilum genetic strains that appear to play an important role in disease events in North American aquaculture facilities and suggest that the practice of trading fish eggs has led to the continental and transcontinental spread of this bacterium. The knowledge generated herein will be invaluable toward guiding the development of future disease prevention techniques.
DOI: 10.1128/aem.02305-18
Institutions: Michigan State University, Agricultural Research Service, United States Department of Agriculture, National Center for Cool and Cold Water Aquaculture, Washington State University, University of Idaho, Université Paris-Saclay, Mathématiques et Informatique Appliquées du Génome à l'Environnement, Utah Division of Wildlife Resources, Pennsylvania Fish and Boat Commission, Alaska Department of Fish and Game, Indiana Department of Natural Resources, University of Wisconsin–Madison, Wisconsin Department of Natural Resources, Minnesota Department of Natural Resources
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Zero hunger
Open Access status: bronze
Awards: G1333315386, G3619213902, G8573866244
OpenAlex ID: W2908911594