Work

Induction of Inflammatory Responses in Splenocytes by Exosomes Released from Intestinal Epithelial Cells followingCryptosporidium parvumInfection

Year: 2019

Type: article

Abstract: Cryptosporidium, a protozoan parasite that infects the gastrointestinal epithelium and other mucosal surfaces in humans and animals, is an important opportunistic pathogen in AIDS patients and one of the most common enteric pathogens affecting young children in developing regions. This parasite is referred to as a “minimally invasive” mucosal pathogen, and epithelial cells play a central role in activating and orchestrating host immune responses.

Source: Infection and Immunity

DOI: 10.1128/iai.00705-18

Authors: Yang Wang, Yujuan Shen, Hua Liu, Jianhai Yin, Xin-Tian Zhang, Ai-Yu Gong, Xiqiang Chen, Siyi Chen, Nicholas W. Mathy, Jianping Cao, Xian-Ming Chen

Institutions: Creighton University, National Institute for Parasitic Diseases, Chinese Center For Disease Control and Prevention

Language: English

Topic: Parasitic Infections and Diagnostics

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Creighton University, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: Epithelial exosomes and TLR-mediated mucosal defense, G1802770337, LincRNAs in Mucosal Defense to AIDS Opportunistic Pathogen Cryptosporidium, Molecular basis of intestinal cryptosporidiosis

OpenAlex ID: W2909422995

FWCI: 4.067

Cites: 51

Cited by: 34

Related to: 10