Work

Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children

Year: 2019

Type: article

Study design: Observational Study

Abstract: genotype and islet autoantibody specificity and with a future diagnosis of T1D. Further, we present a platform to investigate antibacterial antibodies in biological fluids that is applicable to studies of autoimmune diseases and responses to therapeutic interventions.

Source: Science Immunology

DOI: 10.1126/sciimmunol.aau8125

Authors: Alexandra Paun, Christopher Yau, Shahab Meshkibaf, Michelle C. Daigneault, Leili Marandi, Steven Mortin-Toth, Amit Bar-Or, Emma Allen-Vercoe, Philippe Poussier, Jayne S. Danska

Institutions: University of Toronto, Hospital for Sick Children, University of Guelph, Sunnybrook Hospital, Sunnybrook Research Institute, McGill University, University of Pennsylvania

Language: English

Topic: Diabetes and associated disorders

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Juvenile Diabetes Research Foundation United Kingdom, Juvenile Diabetes Research Foundation Canada, Hospital for Sick Children, Canadian Institutes of Health Research, National Institute of Diabetes and Digestive and Kidney Diseases, Breakthrough T1D Canada

Awards: TrialNet: University of Florida Clinical Center and Network, Type 1 Diabetes-A Proposal for Prevention & Intervention, CLINICAL AFFILIATE OF THE TYPE 1 DIABETES TRIALNET, Chicagoland Diabetes TrialNet Clinical Center, Continuation of UCSF as a Clinical Center for TrialNet, Type 1 Diabetes TrialNet Clinical Centers - Kansas City, Prediction and Prevention of Type 1 Diabetes (TrialNet), Northwest Clinical Center for Type 1 Diabetes - TrialNet, G4909115089, Type 1 Diabetes TrialNet: Toronto Clinical Center, NIDDK Type 1 Diabetes TrialNet Data Coordinating Center, TrialNet at Stanford University, Vanderbilt University: Clinical Center Application, Type 1 Diabetes TrialNet, USF TrialNet Clinical Center, Type 1 diabetes TrialNet Center at Yale University, TrialNet: Diabetes Type 1 Prevention, Type 1 Diabetes TrialNet at Indiana University Clinical Center, An Atlanta TrialNet Center: Building a Pathway to 70 Clinical Trial Subjects per Year, Texas Children's Hospital and Baylor College of Medicine TrialNet Clinical Center, Type 1 Diabetes TrialNet Clinical Network Hub

OpenAlex ID: W2912487578

FWCI: 4.89

Cites: 50

Cited by: 58

Related to: 10