Work

Aerosol containment by airflow in biosafety laboratories

Year: 2019

Type: article

Abstract: In this paper, the progress and research related to aerosol containment by airflow in containment environments, e.g., biosafety laboratories, are introduced from a mechanical engineering view. A good air-distribution strategy in the room, a reasonable and stable pressure gradient in the containment area, and a necessary buffer room comprise the integral parts for regulating the air flow and providing the necessary containment. An optimal air-distribution strategy would reduce the residence time of the bio-aerosol in the lab room and lower the exposure risk of the work staff. The pressure difference between adjacent rooms provides sufficient isolation protection when the door is closed. Nevertheless, an unfavorable air exchange would occur when the door is open, owing to door movement, passing people, or a tiny temperature difference. A buffer room is therefore necessary to offset the negative impact and maintain the containment effect.

Source: Journal of Biosafety and Biosecurity

DOI: 10.1016/j.jobb.2018.12.009

Authors: Xin Feng, Yanguo Zhang, Zhonglin Xu, Donglin Song, Guoqing Cao, Lei Liang

Institutions: China Academy of Building Research, Chinese Academy of Sciences, Wuhan Institute of Virology

Language: English

Topic: Infection Control and Ventilation

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $700