Work

A new immunomodulator, FR-900483.

Year: 1988

Type: article

Abstract: FR-900483 is a new immunoactive substance produced by a fungus, Nectria lucida F-4490. Concanavalin A-stimulated lymphocyte proliferation, which had been suppressed by addition of immunosuppressive factor, was restored to a normal level by the addition of FR-900483. Furthermore, FR-900483 restored the capacity of immunosuppressed mice to produce antibody against sheep red blood cells.

Source: The Journal of Antibiotics

DOI: 10.7164/antibiotics.41.296

Authors: TOSHIHIRO SHIBATA, OSAMU NAKAYAMA, YASUHISA TSURUMI, MASAKUNI OKUHARA, HIROSHI TERANO, MASANOBU KOHSAKA

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2917138285

FWCI: 2.903

Cites: 4

Cited by: 59

Related to: 10