Year: 2018
Type: article
Study design: Observational Study
Abstract: Introduction: Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease.Dyslipedemia does not cause symptoms by itself, the symptoms exihibited are the symptoms of the organ or system affected by atherosclerosis.Studies have reported that high cholesterol is present in general and hypertensive population.Study objectives were to study the prevalence of dyslipidemia in newly diagnosed essential hypertension.Material and methods: Newly diagnosed essential hypertensive, whose BP>140/90 mmHg and aged >40 years were included as cases.Age and sex matched normotensive control were included as controls.Routine investigations and Lipid profile was done in all cases and controls.Results: In this study, 50 hypertensive patients were taken as cases and 50 normotensive as controls.The mean systolic BP in the cases was 159±11.98mmHg and in the controls was 116±8.43 mmHg.Out of 50 cases, 20 (40%) patients were dyslipidemic and 30(60%) patients had normal lipid profile.Out of the 50 controls only 12 (24%) had dyslipidemia.Among hypertensive, Serum cholesterol was raised in 5 patients while in controls, only 1 had raised serum cholesterol (p=0.0919).Hypertriglyceridemia was noted in 12 patients in hypertensive and among 7 normotensive (p=0.2031).Raised LDL was found in 4 patients with hypertension and 2 normotensive persons (p=0.3994).HDL was found low in 9 hypertensive and 2 normotensive (p=0.0252).Conclusion: Prevalence of dyslipidemia was higher in patients with essential hypertension than normotensives.Raised serum cholesterol, serum triglyceride and LDL was found in higher frequency in hypertensive than normotensive.Hypertriglyceridimia was the most common lipid abnormality in our study population.The prevalence of dyslipidemia is very high in India, and needs urgent lifestyle intervention strategies to prevent and manage this important cardiovascular risk factor.
Authors: Poonam Gupta, Ajeet Kumar Chaurasia, Anurag Mishra, Gyan Prakash
Institution: Motilal Nehru Medical College
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2920908554