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Arugosins O-Q, New Fungal Metabolites from the Fungus Xylariaceae sp. Isolated from Leaves of Lansium domesticum (Meliaceae)

Year: 2019

Type: article

Abstract: A fungal endophyte which was identified as a hitherto undescribed member of the family Xylariaceae by sequencing of the ITS region was isolated from fresh and healthy leaves of Lansium domesticum collected on tropical peatland of West Kalimantan, Indonesia. Chromatographic separation of the ethyl acetate extract of the fungus resulted in the isolation of three new arugosin type metabolites, including arugosins O (1), P (2), and Q (3). The structures were determined by analysis of 1D and 2D NMR spectra and HRMS data, and by comparison with data from the literature. Biological activities of those compounds are also reported.

Source: Natural Product Communications

DOI: 10.1177/1934578x1901400133

Authors: Rudiyansyah, Andi Hairil Alimuddin, Masriani, Rini Muharini, Zhen Liu, Wenhan Lin, Rudolf Hartmann, Peter Proksch

Institutions: Tanjungpura University, Heinrich Heine University Düsseldorf, Peking University, State Key Laboratory of Natural and Biomimetic Drugs, Forschungszentrum Jülich

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: Bundesministerium für Bildung und Forschung, Direktorat Jenderal Pendidikan Tinggi

OpenAlex ID: W2923923798

FWCI: 0.467

Cites: 24

Cited by: 3

Related to: 10