Work

Immunoadsorption Techniques and Its Current Role in the Intensive Care Unit

Year: 2019

Type: book-chapter

Abstract: Immunoadsorption is an extracorporeal technique used for the removal of antibodies and molecules from the blood. A large number of different adsorbents are now available allowing for the non-selective removal of all subclasses of immunoglobulins such as IgG or more selective removal of disease specific molecules such as lipoprotein(a) and CRP. This selectivity, coupled with its highly efficient removal of the molecule, along with a favourable side-effect profile, has made immunoadsorption an attractive option in a range of autoimmune diseases. Here we discuss the mechanism and technique of immunoadsorption and review the current evidence and indications for its use, particularly in relation to sepsis.

Source: IntechOpen eBooks

DOI: 10.5772/intechopen.84890

Authors: Patrick Hamilton, Rhodri Harris, Sandip Mitra

Institutions: Manchester Academic Health Science Centre, Manchester Royal Infirmary, University of Manchester, Devices for Dignity

Language: English

Topic: Sepsis Diagnosis and Treatment

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Institute for Health and Care Research