Year: 2019
Type: article
Abstract: Nematodes are highly pathogenic and economically important parasites in livestock globally. They strongly challenge the host immunity and in return can be ousted by host via prior anthelmintic treatment. However, this approach is sometimes not appropriate when resistance against anthelmintics develops by these parasites. The problem of parasitism can then be managed by alternative methods where vaccines are thought to play a crucial role. Efforts have been made in past to identify candidate vaccine antigens and are still going on for a wide range of nematode parasite species. The complexities arising due to host-parasite relationship have further challenged scientists to understand mechanisms of vaccine-induced immunity, causing more difficulties in producing effective vaccines though very few vaccines against nematodes have been successfully commercialised. This review highlights some antigens derived from nematode parasites used for the purpose of studying immunoprophylactic responses in livestock.
Authors: Ekta Singh, Dinesh Chandra, Arvind Prasad, Navneet Kaur
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2937250331