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Temozolamide-Associated Pancytopenia in a Patient with Glioblastoma Multiforme

Year: 2019

Type: article

Abstract: Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. GBM treatment is a combined modality approach involving maximum surgical resection, adjuvant postoperative radiation and adjuvant chemotherapy treatment.There is a greater risk of hematological toxicity in concurrent temozolomide and radiation therapy. We reported that pancytopenia has been developed on a 54-year old female patient with GBM after concurrently used temozolomide and radiotherapy treatment. It should be kept in mind that this side effect may develop because the risk of morbidity and mortality may be elevated. Therefore, supportive therapies should be started immediately in patients where this toxicity developed.

Source: International Journal of Case Reports

DOI: 10.28933/ijcr-2019-03-2106

Authors: Bozkurt, Kübra, TERZİ DEMİRSOY, ESRA, TÜRKMEN BEKMEZ, ESMA, AYDIN, DİNÇER

Institutions: Sağlık Bilimleri Üniversitesi, Health Sciences University Derince Training and Research Hospital

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2942321828