The association of serum copper with ceruloplasmin and zinc with folic acid levels in recurrent pregnancy loss in Iraqi Women
Year: 2019
Type: article
Study design: Observational Study
Abstract: Background and Objectives: Recurrent pregnancy loss (RPL) is the most common adverse pregnancy outcome. Micronutrients include minerals and vitamins are essential for normal function, growth, and development. Minerals have important effects on the health of the mother and the fetus. Micronutrient deficiency during pregnancy can lead to obstetric complications and even fetal death. Materials and Methods: A total of 90 pregnant women included in this study were between 7 and 20 weeks of gestation, their age was 18–40 years, and they were divided into three main groups. Patients: Group 1, pregnant women diagnosed with missed miscarriage no = 30; Controls: Group 2, ongoing pregnancy no = 30; and Group 3, nonpregnant women no = 30. Serum copper (Cu) and zinc (Zn) were determined using flame atomic absorption spectrometry. While the serum ceruloplasmin (CP) was measured by immunoturbidimetric assay and folic acid (FA) by enzyme-linked immune sorbent assay. Results: Serum Cu and CP were significantly higher in the women with RPL compared with healthy groups. Moreover, the levels of Zn were significantly lower in in women with RPL compared with healthy control groups, and the result of serum FA was showed that there no significant variation in patients with RPL compared with control groups. Conclusions: The study showed that the alteration in the trace elements could participate with the RPL.
Source: Mustansiriya Medical Journal
DOI: 10.4103/mj.mj_41_18
Institution: Mustansiriyah University
Language: English
Topic: Trace Elements in Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2944562967