Work

Oxidative Stress and Polycystic Ovary Syndrome: A Brief Review

Year: 2019

Type: review

Abstract: Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders, occurring in 5-10% women in reproductive ages. Despite a long history of studies on PCOS, its etiology is still unknown. Oxidative stress is now recognized to play a central role in the pathophysiology of many different disorders, including PCOS. Although intracellular reactive oxygen species (ROS) production and propagation are controlled by highly complex antioxidant enzymatic and non-enzymatic systems, understanding of mechanisms that oxidative stress is important to develop strategies for prevention and therapy of PCOS. This article reviews the literature data related to the mechanisms of oxidative stress in PCOS.

Source: International Journal of Preventive Medicine

DOI: 10.4103/ijpvm.ijpvm_576_17

Author: Masoumeh Mohammadi

Institutions: Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences

Language: English

Topic: Ovarian function and disorders

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $78