A Convenient Synthesis of 3-Benzoylisoxazoles by 1,3-Dipolar Cycloaddition
Year: 2002
Type: article
Abstract: A convenient, efficient method for the preparation of 3-benzoylisoxazoles is described.Nitrile oxides generated in situ from phenylglyoxylohydroxamyl chlorides and NaHCO 3 in isopropyl alcohol smoothly react with dipolarophiles at room temperature to provide the cycloadducts.
Source: Heterocycles
DOI: 10.3987/com-02-9618
Authors: Hiroyuki Kai, Minoru Tomida, Toru Nakai, Akira Takase
Institution: Shionogi (Japan)
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W2950848337