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Disulfoxide Ligands in Rhodium Catalyzed Asymmetric 1,4-Addition: First Studies and Future Directions

Year: 2009

Type: article

Abstract: Disulfoxides with atropisomeric backbones are introduced as readily available chiral ligands for the rhodium-catalyzed 1,4-addition of arylboronic acids to unsaturated carbonyl compounds. The ligands are obtained in pure form from either commercially available or easily synthesized starting materials. Precatalysts with general formula {(disulfoxide)RhCl}2 were prepared in high yield and were fully characterized. Preliminary results on the influence of steric and electronic modifications of the ligand structure and their impact on the catalytic behavior are presented.

Source: CHIMIA International Journal for Chemistry

DOI: 10.2533/chimia.2009.508

Authors: Ronaldo Mariz, Justus Bürgi, Michele Gatti, Emma Drinkel, Xinjun Luan, Reto Dorta

Institution: University of Zurich

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Universität Zürich

OpenAlex ID: W2952640596

FWCI: 0.151

Cites: 6

Cited by: 5

Related to: 10