Work

Dual admittance catheter-derived biventricular pressure-volume analysis in swine: comparison with contrast-enhanced computed tomography during transient pressure overload

Year: 2019

Type: other

Abstract: We have compared biventricular Pressure-Volume Analysis in Swine with Contrast-Enhanced Computed Tomography During Transient Pressure Overload. Pressure overload was induced by 60-minute intravenous infusion of phenylephrine (PE; 300 ug/min). Biventricular PV analysis provided reasonably accurate measurements of ventricular volumes compared with contrast-enhanced cardiac multi-detector computed tomography (MDCT). Employing this approach during transient PE infusion demonstrated persistent chamber dilatation and systolic dysfunction in the LV, but not RV, consistent with stretch-induced stunning caused by an acute elevation in preload.

DOI: 10.7490/f1000research.1116595.1

Authors: Filip Konecny, Cody Smith, George Techiryan, John M Canty Jr., Brian R Weil

Institutions: Transonic Systems (United States), McMaster University, University at Buffalo, State University of New York

Language: English

Topic: Cardiovascular Function and Risk Factors

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W2955410445

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