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Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity

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Year: 2019
Type: article
Source: Bioorganic & Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2019.07.039
Authors: Tsuyoshi Saitoh, Kazunori Seki, Ryo Nakajima, Naoshi Yamamoto, Noriki Kutsumura, Yasuyuki Nagumo, Yoko Irukayama-Tomobe, Yasuhiro Ogawa, Yukiko Ishikawa, Ryuji Tanimura, Masashi Yanagisawa, Hiroshi Nagase
Institutions: University of Tsukuba, International Institute for Integrative Sleep Medicine, University of Tsukuba, Toray Industries, Inc. (Japan), The University of Texas Southwestern Medical Center
Language: English

Topic: Neuropeptides and Animal Physiology
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Japan Foundation for Applied Enzymology, Ministry of Education, Culture, Sports, Science and Technology, Japan Society for the Promotion of Science
Awards: Elucidation of molecular mechanism of cognitive dysfunction associated with sepsis and approach to new therapeutic agents, Development of novel photochemical tools to regulate wakefulness
OpenAlex ID: W2963354076
FWCI: 0.696
Cites: 17
Cited by: 11
Related to: 10
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