Work

Simulated Microgravity Condition Alters the Gene Expression of some ECM and Adhesion Molecules in Adipose Derived Stem Cells.

Year: 2018

Type: article

Abstract: genes. ColIII protein levels also increased. There were no significant changes in the viability of cells cultured in microgravity. Since the high expression of ECM components is known as one of the fibroblast markers, our data suggest that pretreatment of ADSCs by simulated microgravity may increase their differentiation capacity towards fibroblastic cells. Microgravity had not adversely affected the viability of ADSCs, and it is likely to be used alone or in combination with biochemical inducers for cell manipulation.

Source: PubMed Central

DOI: 10.22088/ijmcm.bums.7.3.146

Authors: Farid Ebnerasuly, Zahra Hajebrahimi, Seyed Mehdi Tabaie, Mojtaba Darbouy

Institutions: Islamic Azad University, Marvdasht, Aerospace Research Institute, Ministry of Science, Research and Technology, Academic Center for Education, Culture and Research

Language: English

Topic: Spaceflight effects on biology

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2963530684

FWCI: 2.186

Cites: 44

Cited by: 25

Related to: 10