Work

Peripheral hypertrophic subepithelial corneal degeneration: clinical aspects related to in vivo confocal microscopy and optical coherence tomography

Year: 2019

Type: article

Abstract: PURPOSE: To report the findings of anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM) in two patients with peripheral hypertrophic subepithelial corneal degeneration (PHSD). METHODS: Case series by restrospective chart review and imaging analysis of AS-OCT and IVCM. RESULTS: Slit lamp examination of the two patients revealed a bilateral subepithelial-elevated fibrous tissue of the superior-nasal quadrant, as well as inferior-nasal in one of the patients. Best corrected visual acuity ranged from 20/25 to 20/15. AS-OCT showed continuous, homogenous, well-demarked hyperreflective subepithelial band associated with hyperreflectivity in the anterior stroma. IVCM demonstrated normal epithelial cell morphology and arrangement and a fibrous structure subepithelial and in the anterior stroma. CONCLUSION: AS-OCT and IVCM can facilitate the diagnosis of PHSD and differentiate it from other corneal entities that present peripheral opacifications.

Source: International Medical Case Reports Journal

DOI: 10.2147/imcrj.s208297

Authors: Jeanne Martine Gunzinger, Nafsika Voulgari, Aleksandra Petrovic, Kattayoon Hashemi, Georgios Kymionis

Institutions: Hôpital Ophtalmique Jules-Gonin, University of Lausanne

Language: English

Topic: Corneal surgery and disorders

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,320