The VirAB-VirSR-AnrAB Multicomponent System Is Involved in Resistance of Listeria monocytogenes EGD-e to Cephalosporins, Bacitracin, Nisin, Benzalkonium Chloride, and Ethidium Bromide
Year: 2019
Type: article
Abstract: EGD-e. The modules consist of the VirSR TCS and the VirAB and AnrAB ABC transporters. Our results showed that this system is involved in nisin and bacitracin resistance, as well as resistance to cephalosporins, ethidium bromide (EtBr), and benzalkonium chloride (BC). In this system, VirAB is responsible only for antimicrobial sensing and signaling by VirSR, while AnrAB contributes to transportation of antimicrobials. Interestingly, VirAB itself, rather than the VirAB-VirSR-AnrAB system as a whole, contributes to kanamycin and tetracycline resistance.
DOI: 10.1128/aem.01470-19
Authors: Xiaobing Jiang, Yimin Geng, Siyu Ren, Tao Yu, Yi Li, Guosheng Liu, Hailei Wang, Hecheng Meng, Lei Shi
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Award: G3527429697
OpenAlex ID: W2964684263