Work

Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

Year: 2019

Type: article

Abstract: animals that received neonatal GM-CSF were protected from experimental pneumococcal challenge. No detrimental effects on surfactant metabolism or alveolarization were observed. Airway recombinant GM-CSF administration thus shows therapeutic promise to accelerate neonatal pulmonary immunity, protecting against bacterial pneumonia.

Source: Science Advances

DOI: 10.1126/sciadv.aax3387

Authors: Elizabeth M. Todd, Rashmi Ramani, Taylor P. Szasz, S. Celeste Morley

Institution: Washington University in St. Louis

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500