Work

Synthesis of Uracil-Iodonium(III) Salts for Practical Utilization as Nucleobase Synthetic Modules

Year: 2019

Type: article

Abstract: Iodonium(III) salts bearing uracil moieties have recently appeared in the literature, but their structural scope and utilization are limited because of their hygroscopic characteristics. In this study, we describe our detailed investigations for synthesizing a series of uracil iodonium(III) salts derived with various structural motifs and counterions. These new compounds have been utilized as attractive synthetic modules in constructing functionalized nucleobase and nucleosides

Source: Molecules

DOI: 10.3390/molecules24173034

Authors: Naoko Takenaga, Takumi Hayashi, Shohei Ueda, Hiroyuki Satake, Yoichi Yamada, Tetsuya Kodama, Toshifumi Dohi

Institutions: Meijo University, Ritsumeikan University, Kanagawa University of Human Services, Shujitsu University, Nagoya University

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,824

Funder: Japan Society for the Promotion of Science

Awards: Development of Efficient Aromatic C-H Amination method Using Highly Reactive Hypervalent Iodine Catalyst, Development of new transformation of polycyclic aromatic compounds utilizing reactive carbon-iodine(III) bond

OpenAlex ID: W2969937200

FWCI: 0.364

Cites: 57

Cited by: 11

Related to: 10