Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia
Year: 2019
Type: article
Abstract: by downregulating the expressions of caspase-3 and NF-кB mRNA during ischemia and reperfusion and that of p38 and caspase-3 during acute ischemia and reperfusion as well as the steady-state levels of excitatory amino acids/inhibitory amino acids and by improving the total antioxidant capacity and total superoxide dismutase activities during ischemia. These findings provide new molecular evidence for the mechanisms underlying ZXC action.
Source: Frontiers in Pharmacology
Authors: Xia Wei, Qingfen Zhu, Na Liu, Lihua Xu, Sheng Wei, Zhiyun Fan, Changhua Sun, Yan Zhao, Mingqi Qiao, Jibiao Wu, Defu Hu, Yang Wang, Peng Sun
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,950
OpenAlex ID: W2970943289