EP18.20: Middle cerebral artery peak systolic velocity can be a parameter for fetal abnormal condition in cases of fetal growth restriction
Year: 2019
Type: conference-abstract
Abstract: Although elevation of middle cerebral arterial peak systolic velocity (MCA-PSV) is known as a sign of fetal anemia, limited have been reported on other clinical values. The aim of this study is to investigate the benefit of measuring of MCA-PSV in cases of fetal growth restriction (FGR). This retrospective study included 248 fetuses who were diagnosed FGR at our hospital from June 2008 to December 2016 and delivered at our hospital. We defined high MCA-PSV as the value exceeding 1.5 multiple of median (MoM), and assigned the case to high MCA-PSV group when we found high MCA-PSV at least one time. We compared the perinatal prognosis of high MCA-PSV group and normal MCA-PSV group. The primary outcome was the frequency of emergency Caesarean section (CS), and the secondary outcomes were as follows: gestational age at delivery, birth weight, Apgar score, pH and base excess (BE) of umbilical cord arterial blood gas and the rate of NICU admission. The numbers of high MCA-PSV group and normal MCA-PSV group were 18 cases (7.3%) and 230 cases (92.7%) respectively. The range of gestational week when we measured MCA-PSV was from 20 weeks to 42 weeks, and the average was 33.1 weeks. The frequency of CS was higher in high MCA-PSV group (61.1% vs. 29.1%, p = 0.007). In high MCA-PSV group, gestational age at delivery was earlier (34.9 weeks vs. 37.0 weeks, p = 0.007) and birth weight was also lower (1559 g vs. 2106 g, p < 0.001). The median of Apgar scores were lower (1-minute: 5 vs. 8, p = 0.002 and 5-minute: 8.5 vs. 9, p < 0.001) and the rate of NICU admission was higher (88.5% vs. 60.1%, p = 0.002) in high MCA-PSV group. And, pH (7.255 vs. 7.267, p = 0.594) and BE (-3.95 vs. -3.50, p = 0.73) of umbilical cord arterial blood gas did not show significant difference. In cases of FGR, there was correlation between high MCA-PSV and perinatal short prognosis. Measuring MCA-PSV can be effective in assessing the fetal condition. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
DOI: 10.1002/uog.21497
Authors: T. Ueno, A. Morio, T. Shibata, T. Yamada, T. Takeda, S. Tano, K. Uno, T. Suzuki, T. Harata, T. Izawa, Y. Kishigami, H. Oguchi
Institution: Toyota Memorial Hospital
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2977720784