Association between anthropometric indices of obesity and risk of cardiovascular disease in Japanese men
Year: 2019
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: We aimed to compare the association of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) with risk of cardiovascular disease (CVD) among middle-aged working Japanese men. METHODS: A nested case-control study was performed among middle-aged male employees who underwent periodic health checkup. A total of 241 CVD cases were identified and matched individually on age, gender, and worksite with 1205 controls. Data on BMI, WC, WHtR, smoking, hypertension, diabetes, and dyslipidemia collected at 4 years before the event/index date were retrieved. Associations between BMI, WC, WHtR, and CVD risk were assessed by using conditional logistic regression models. RESULTS: The strength of the association of BMI, WC, and WHtR with CVD risk was similar. The smoking-adjusted odds ratio (95% confidence interval) for CVD was 1.60 (1.38-1.85), 1.53 (1.33-1.78), and 1.56 (1.35-1.81) for a 1 SD unit increase in BMI, WC, and WHtR respectively. After further adjustment for hypertension, diabetes, and dyslipidemia, these associations were attenuated but remained statistically significant. CONCLUSIONS: Measures of general (BMI) and abdominal (WC and WHtR) obesity were similarly associated with CVD in middle-aged Japanese men.
Source: Journal of Occupational Health
Authors: Mi Xiang, Huanhuan Hu, Teppei Imai, Akiko Nishihara, Naoko Sasaki, Takayuki Ogasawara, Ai Hori, Tohru Nakagawa, Shuichiro Yamamoto, Toru Honda, Hiroko Okazaki, Akihiko Uehara, Makoto Yamamoto, Toshiaki Miyamoto, Takeshi Kochi, Masafumi Eguchi, Taizo Murakami, Makiko Shimizu, Kentaro Tomita, Satsue Nagahama, Akiko Nanri, Maki Konishi, Shamima Akter, Keisuke Kuwahara, Ikuko Kashino, Miwa Yamaguchi, Isamu Kabe, Tetsuya Mizoue, Naoki Kunugita, Seitaro Dohi, Y Inoue, A Fukunaga, Z Islam, K Kurotani, Y Watanabe, T Ogasawara, M Hasegawa, M Shirozu, C Shimizu, N Gonmori, A Ogasawara, N Kato, A Tomizawa, T Sone, K Fukasawa, C Nishiura, C Kinugawa, R Kuroda, K Yamamoto, M Ohtsu, N Sakamoto, Y Osaki, T Totsuzaki, M Endo, T Itoh, M Kawashima, M Masuda, K Kitahara, T Yokoya, K Fukai, K Odagami, Y Kobayashi
Institutions: National Center for Global Health and Medicine, Azbil (Japan), Mitsubishi Fuso Truck and Bus (Japan), University of Tsukuba, Hitachi (Japan), Mitsui Chemicals (Japan), Teikyo University Hospital, Mizonokuchi, Shinseikai-Toyama Hospital, Nippon Steel (Japan), Furukawa Electric (Japan), Keihin (Japan), Mitsubishi Plastics (Japan), All Japan Labor Welfare Foundation, Fukuoka Women's University, Teikyo University, National Institute of Public Health
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,250
OpenAlex ID: W2990950709