Equine Insulin Dysregulation and Laminitis: Developing a Framework for Testing Treatment and Preventive Strategies
Year: 2019
Type: dissertation
Abstract: Insulin-associated laminitis is a deadly and currently incurable disease of the horse's hoof. This project developed a series of new methods to cause laminitis experimentally, to accurately grade the severity of the disease, and to determine the risk of an individual horse developing the condition. Additionally, a novel drug treatment (velagliflozin) was shown to be able to prevent laminitis, and to be safe and effective when used for several months. If it is successful in reaching the market, velagliflozin will be the first veterinary treatment to be registered for this disease.
Author: Alexandra D Meier
Language: English
Subfield: Equine
Field: Veterinary
Domain: Health Sciences
Open Access status: green
Funder: Massey University
OpenAlex ID: W2990969916