Work

Appropriate endpoints for stereotactic body radiotherapy for bone metastasis: Classification into five treatment groups

Year: 2019

Type: review

Abstract: Treatment of bone metastasis using stereotactic body radiotherapy (SBRT) is being widely used in clinical practice. The reported clinical advantages of SBRT include high pain and local control rates, high response rates against bone metastasis from radio-resistant tumors, and safe re-irradiations. Although most reports in the literature use local control as the primary treatment endpoint, this endpoint is not appropriate because local control does not relate directly to patient benefit. Herein, we proposed five pathophysiology-based patient groups, as well as appropriate endpoints for each group.

Source: Reports of Practical Oncology & Radiotherapy

DOI: 10.1016/j.rpor.2019.12.018

Authors: Kei Ito, Naoki Nakamura, Takuya Shimizuguchi, Hiroaki Ogawa, Katsuyuki Karasawa

Institutions: Tokyo Metropolitan Komagome Hospital, National Cancer Center Hospital East

Language: English

Topic: Management of metastatic bone disease

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,500