Vibrio cholerae Virulence Activator ToxR Regulates Manganese Transport and Resistance to Reactive Oxygen Species
Year: 2019
Type: article
Abstract: Like many other pathogens, Vibrio cholerae , the causative agent of cholera, can modulate its gene expression to combat stresses encountered in both aquatic and host environments, including stress posed by reactive oxygen species (ROS). We previously reported that the virulence activator AphB in V. cholerae is involved in ROS resistance. In this study, we found that another key virulence regulator, ToxR, was important for V. cholerae resistance to hydrogen peroxide.
Source: Infection and Immunity
DOI: 10.1128/iai.00944-19
Authors: Hang-hang Jiang, Yitian Zhou, Ming Liu, Jessie Larios-Valencia, Zachariah Lee, Hui Wang, Xing-Hua Gao, Jun Zhu
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2998020331