Year: 2020
Type: article
Study design: Case Report
Abstract: A case of fungal keratitis due to Coprinellus radians is reported. To our knowledge, fungal keratitis caused by this species was rare. Fungal hyphae were detected in corneal scrapings, and isolates were identified by morphology and by sequencing the internal transcribed spacer region of ribosomal DNA. The patient was treated with systemic and local antifungal therapy for 5 days, and lamellar keratoplasty was performed after no obvious improvement in symptoms. The in vitro antifungal susceptibilities of the case strain were tested for six antifungal agents. The results showed that 5-fluorouracil was resistant, fluconazole was moderately sensitive, and the other drugs assayed (amphotericin B, posaconazole, itraconazole and voriconazole) were highly effective against this fungus.
Source: Mycopathologia
Authors: Xiuhai Lu, Xin Wang, Li Zhang, Xiaofeng Li, Xiaolin Qi
Institutions: Shandong Eye Hospital, Shandong First Medical University
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,260
Awards: G1794500329, G2670740794, G6535803593
OpenAlex ID: W3000299526