Year: 2020
Type: review
Abstract: Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g., morphea, sclerodactyly, scleroderma in bands). Besides, it was reported that it can improve the mood and quality of life of postmenopausal women in reducing menopause-related symptoms. This article aims to summarize the studies on biological effects of the avocado-soybean unsaponifiable, its chemical composition, pharmacotherapy as well as applications in auto-immune, osteoarticular and menopausal disorders. Finally, we will also discuss on its safety, toxicological and regulatory practices.
Source: Biomolecules
DOI: 10.3390/biom10010130
Institutions: Bam University of Medical Sciences, University of Cagliari, University of Medicine and Pharmacy of Craiova, G.B. Pant Institute of Himalayan Environment and Development, Bayburt University, Istanbul Technical University, Universal Scientific Education and Research Network, Shahid Beheshti University, Shahid Beheshti University of Medical Sciences, Tajik State Medical University, Queen Elizabeth Hospital, Universidade do Porto, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Language: English
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,901
OpenAlex ID: W3000608153