Work

Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

Year: 2020

Type: article

Abstract: The synthesis and photophysical properties of a new class of α-amino acid bearing a rigid pyrazoloquinazoline chromophore are described. Confromational constraint of the amino acid side-chains resulted in high emission quantum yields, while the demonstration of two-photon-induced fluorescence via near-IR excitation signifies their potential for sensitive bioimaging applications.

Source: Chemical Communications

DOI: 10.1039/c9cc09064a

Authors: Jonathan D. Bell, Alexander H. Harkiss, David Nobis, Eilidh Malcolm, Astrid Knuhtsen, Christopher R. Wellaway, Andrew G. Jamieson, Steven W. Magennis, Andrew Sutherland

Institutions: University of Glasgow, GlaxoSmithKline (United Kingdom)

Language: English

Topic: Luminescence and Fluorescent Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Funders: GlaxoSmithKline, University of Glasgow, Engineering and Physical Sciences Research Council

Awards: Substrate Peptidomimetic Inhibitors (SPIs) of the COP9 signalosome, Industrial CASE Account - University of Glasgow 2015, G6194943492, DTA - University of Glasgow

OpenAlex ID: W3000746252

FWCI: 1.654

Cites: 46

Cited by: 27

Related to: 10