Work

Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana

Year: 2020

Type: article

Study design: Observational Study

Abstract: < 0.001), respectively. IgG1 and/or IgG3 subclasses against five antigens from these subsets were associated with protection. Through this comparative study, maintaining uniformity of reagents and methodology, we demonstrate that NAI across diverse geographic regions may result from antibodies to multiple antigenic targets that constitute the peripheral merozoite surface protein complexes.

Source: Infection and Immunity

DOI: 10.1128/iai.00778-19

Authors: Asier Garcia-Senosiain, Ikhlaq Hussain Kana, Susheel Kumar Singh, Bishwanath Kumar Chourasia, Manoj Kumar Das, Daniel Dodoo, Subhash Singh, Bright Adu, Michael Theisen

Institutions: Statens Serum Institut, University of Copenhagen, Copenhagen University Hospital, Rigshospitalet, Indian Institute of Integrative Medicine, National Institute of Malaria Research, University of Ghana, Noguchi Memorial Institute for Medical Research

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Strategiske Forskningsråd, Department of Biotechnology, Ministry of Science and Technology, India, Udenrigsministeriet, European and Developing Countries Clinical Trials Partnership

Awards: G2347546863, G3078755207, G4625266299, G6468178243, G7106845835

OpenAlex ID: W3001263409

FWCI: 2.012

Cites: 46

Cited by: 21

Related to: 10