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Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug

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Year: 2020
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01420
Authors: Sung Hu, Mariarosaria Ferraro, Ajesh P. Thomas, Jeong Min Chung, Nam Gu Yoon, Ji-Hoon Seol, Sangpil Kim, Han-ul Kim, Mi Young An, Haewon Ok, Hyun Suk Jung, Ja-Hyoung Ryu, Giorgio Colombo, Byoung Heon Kang
Institutions: Ulsan National Institute of Science and Technology, Institute of Chemistry of Molecular Recognition, National Research Council, Kangwon National University, University of Pavia
Language: English

Topic: Heat shock proteins research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Ulsan National Institute of Science and Technology, National Research Foundation of Korea, Associazione Italiana per la Ricerca sul Cancro, Neurofibromatosis Therapeutic Acceleration Program
Awards: G2064820571, G3053029259, G3900687761, G4833210105, G5826064285, G7062671208, G7938569998
OpenAlex ID: W3008028016
FWCI: 1.286
Cites: 41
Cited by: 27
Related to: 10
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