Work

Targeting the eIF4E/β-catenin axis sensitizes cervical carcinoma squamous cells to chemotherapy.

Year: 2017

Type: article

Abstract: . Our findings demonstrate that eIF4E/β-catenin signaling plays a positive regulatory role in the resistance of cervical cancer cell to chemotherapy and thus highlight the therapeutic value of eIF4E or β-catenin inhibition in overcoming chemoresistance.

Source: PubMed Central

Authors: Hai Xu, Zhiyin Wang, Lang Xu, Guoyan Mo, Gangfeng Duan, Yali Wang, Zhengang Sun, Hao Chen

Institutions: Hubei University of Chinese Medicine, Wuhan University of Science and Technology, Wuhan City Chinese Medicine Hospital, Wuhan General Hospital of Guangzhou, Yangtze University, Jingzhou Central Hospital

Language: English

Topic: Wnt/β-catenin signaling in development and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3010076376

FWCI: 1.266

Cites: 25

Cited by: 19

Related to: 10