Work

New Delhi Metallo-beta-lactamase-producing Enterobacter Cloacae – A Rare Multidrug Resistance Strain in a Caucasian Woman

Year: 2020

Type: article

Abstract: New Delhi metallo-beta-lactamase (NDM-1) is a novel metallo-beta-lactamase (MBL) gene carried by some Enterobacteriaceae that induces resistance to most of the antibiotics. First described in a Swedish patient hospitalized in India with an infection due to Klebsiella pneumoniae. NDM-1 makes bacteria resistant to a broad range of beta-lactam antibiotics. These include the antibiotics of the carbapenem family, which are a mainstay for the treatment of antibiotic-resistant bacterial infections. Most of these carbapenem resistant Enterobacteriaceae (CRE) are increasingly recognized in hospital settings and post-acute care settings like long-term acute care settings. Percentage of CRE infections is increasing in the United States of America, and invasive infections with CRE carry high mortality rates and limited treatment options. We here present a rare case of elderly Caucasian woman with CRE cellulitis of both legs with no travel history.

Source: Cureus

DOI: 10.7759/cureus.7177

Authors: Suman Siddamreddy, Sreenath Meegada, Vasuki Dandu, Vijayadershan Muppidi, Ramya Bachu

Institutions: Indiana University Health, Indiana University Hospital, Baptist Health Foundation, University of Arkansas for Medical Sciences

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W3010454405