Work

Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst

Year: 2020

Type: article

Abstract: This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic yields are achieved in short reaction times and produced in solvent-free conditions, which lead to a more environmentally friendly process.

Source: ACS Omega

DOI: 10.1021/acsomega.0c00369

Authors: Mahmoud Abd El Aleem Ali Ali El-Remaily, Ahmed M. M. Soliman, Omar M. Elhady

Institution: Sohag University

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: gold

Estimated APC paid: $750