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Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Returnees to Japan from Wuhan, China, 2020

Year: 2020
Type: article
Study design: Observational Study
Abstract: W ith the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, several countries, including Japan, repatriated their nationals (1-3).During January 29-31, 2020, a total of 566 Japanese nationals were repatriated via 3 chartered flights from Wuhan (206, 210, and 150 passengers).After passengers disembarked in Tokyo, Japan, quarantine officials assessed them for signs/symptoms (e.g., fever, respiratory illness) of coronavirus disease (COVID-19) (4).A total of 28 symptomatic passengers were transferred to select hospitals for isolation.The remaining 538 were transported to a designated hospital, where another 35 were found to be symptomatic and were hospitalized there or transferred to other hospitals, leaving 503 asymptomatic persons for observation in quarantine (Figure ). The StudyWe conducted day 1 entry screening by testing oropharyngeal swab samples collected from all 566 returnees at the hospitals to which they were initially transported for SARS-CoV-2 (4); all tests were based on the real-time reverse transcription PCR developed by the National Institute of Infectious Diseases (5).Hospitalized patients in isolation and asymptomatic returnees in quarantine were monitored daily for 14 days.If any signs/symptoms developed in a quarantined person, that person was transported to a designated hospital and oropharyngeal swab samples were collected for testing.We conducted exit screening for quarantined persons who remained illness-free by collecting oropharyngeal swab samples on day 14.The National Institute of Infectious Diseases Ethics Committee approved the study (registration no.1096), and all 566 returnees who provided specimens gave written informed consent.Among the 63 passengers who were symptomatic at entry screening, 2 (3.2%) were positive by PCR Severe Acute Respiratory Syndrome Coronavirus 2 Infectionamong Returnees to Japan from Wuhan, China, 2020
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W3015203085
FWCI: 1.048
Cites: 14
Cited by: 32
Related to: 10