Year: 2020
Type: article
Abstract: Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID-19.
Source: Arthritis & Rheumatology
DOI: 10.1002/art.41285
Authors: Lauren A. Henderson, Scott W. Canna, Grant S. Schulert, Stefano Volpi, Pui Y. Lee, Kate F. Kernan, Roberto Caricchio, Shawn Mahmud, Melissa M. Hazen, Olha Halyabar, Kacie J. Hoyt, Joseph Han, Alexei A. Grom, Marco Gattorno, Angelo Ravelli, Fabrizio De Benedetti, Edward M. Behrens, Randy Q. Cron, Peter A. Nigrovic
Institutions: Boston Children's Hospital, Harvard University, University of Pittsburgh, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Istituto Giannina Gaslini, University of Genoa, Temple University Hospital, University of Minnesota, University of Minnesota Medical Center, Icahn School of Medicine at Mount Sinai, Bambino Gesù Children's Hospital, Children's Hospital of Philadelphia, University of Pennsylvania, Children's of Alabama, University of Alabama at Birmingham, Brigham and Women's Hospital
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: Medical School, University of Minnesota, Rheumatology Research Foundation, Lupus Research Alliance, Fundación Bechara, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1119439894, G1479298936, G1555854903, The Reprogramming of Regulatory T cells to a Th17 Phenotype in Systemic Juvenile Idiopathic Arthritis, G1753749282, G2106887844, G2557078334, G325620603, G38844304, T resident memory cells in arthritis, Ly6 family members in neutrophil biology, G7386455673, Inflammation Phenotypes in Pediatric Sepsis Induced Multiple Organ Failure Renewal, Joint Biology Consortium Resource-based Center, Bridging the gap between GWAS and mechanism in arthritis, G973016125
OpenAlex ID: W3015607499