Work

Glioblastoma Occurred 20 Years after Cerebrospinal Irradiation: Case Report and Literature Review

Year: 2020

Type: article

Abstract: Radiation-induced gliomas represent a relatively rare but well-characterized entity in the neurooncologic literature.Age-related cerebral vulnerability could be a specific factor in the genesis of these complications.The occurrence of a malignant glioma at the site of a preexisting medulloblastoma is exceptional.Our purpose is to review the literature regarding the role of radiotherapy (RT) in the treatment of patients with radiation-induced malignant gliomas (RIMGs) These findings support the notion that radiation-induced GBM should be considered a distinct clinical entity.Further understanding of multiple genetic changes after radiation will help protect patients who have already been cured of their original malignancy.

Source: World Journal of Innovative Research

DOI: 10.31871/wjir.8.3.40

Authors: S.H TOUIMI, I MBARKI, H ELKACEMI, S ELMAJJAOUI, T KEBDANI, N BENJAAFAR

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W3017366937

FWCI:

Cites: 24

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Related to: 10