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Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase

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Year: 2020
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02035
Authors: Volker K. Schulze, Ulrich Klar, Dirk Kosemund, Antje M. Wengner, Gerhard Siemeister, Detlef Stöckigt, Roland Neuhaus, Philip Lienau, Benjamin Bader, Stefan Prechtl, Simon J. Holton, Hans Briem, Tobias Marquardt, Hartmut Schirok, Rolf Jautelat, Rolf Bohlmann, Duy Nguyen, Amaury E. Fernández-Montalván, Ulf Bömer, Uwe Eberspaecher, Michael Brüning, Olaf Döhr, Marian Raschke, Bertolt Kreft, Dominik Mumberg, Karl Ziegelbauer, Michael Brands, Franz von Nussbaum, Marcus Koppitz
Institution: Bayer (Germany)
Language: English

Topic: Microtubule and mitosis dynamics
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W3019818403
FWCI: 3.202
Cites: 22
Cited by: 60
Related to: 10
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