Get started
Work

Mp76-18 Etiology of Testicular Masses According to Tumor Size. Criteria to Decide Conservative Surgery?

Year: 2020
Type: article
Study design: Observational Study
Abstract: You have accessJournal of UrologyPenile & Testicular Cancer: Penile & Testicular Cancer III (MP76)1 Apr 2020MP76-18 ETIOLOGY OF TESTICULAR MASSES ACCORDING TO TUMOR SIZE. CRITERIA TO DECIDE CONSERVATIVE SURGERY? Gema del Pozo Jiménez*, Ignacio Castillón Vela, Jorge Turo Antona, Alfonso Gimeno Collado, and Joaquin Carballido Rodríguez Gema del Pozo Jiménez*Gema del Pozo Jiménez* More articles by this author , Ignacio Castillón VelaIgnacio Castillón Vela More articles by this author , Jorge Turo AntonaJorge Turo Antona More articles by this author , Alfonso Gimeno ColladoAlfonso Gimeno Collado More articles by this author , and Joaquin Carballido RodríguezJoaquin Carballido Rodríguez More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000962.018AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The small testicular masses have benignity rates of 60-80% and could be candidates for conservative surgery (CS). However, there is no defined limit of tumor size (TS) that predicts the likelihood of a benign finding. The objective is to determine the proportion of benign histology in different ranges of testicular TS. METHODS: Retrospective analysis of 100 patients with testicular tumor diagnosis between January 2011 and October 2018 with a median follow-up of 27.5 months. Radical orchiectomy was performed in 90%, with four cases of CS. Demographic, clinical and pathological variables were collected. TS was defined as the maximum diameter objectified in testicular ultrasound. The proportion of benign findings was determined at different TS cutoff levels: ≤ 10, 11-20 and> 20 mm. A Chi square test was performed to determine the association between TS and the proportion of benign histology, considering statistical significance as p <0.05. A ROC curve was elaborated and the area under it (AUC) was calculated to determine the optimal TS cut-off point in which the benignity rate would be higher. RESULTS: The mean age at diagnosis was 35.5 years. Lesions were benign in 20% (the most frequent tumors of Leyding cells, as reflected in Table 1), being 85% non-palpable (p <0.001). The TS mean for benign and malignant lesions was 9.5 and 38.6 mm, respectively, showing a statistically significant association between small testicular lesions and benign histology (p <0.0001). In the ROC curve it was observed that 10 mm was the cut-off point of TS to predict benign versus malignant histology, with sensitivity and specificity of 98.4 and 71% respectively, as well as AUC of 0.945 (95% CI 0.85 -1) with p <0.0001 (Graphic 1). 94% of lesions <10 mm were benign, while above this TS, only 2%. CONCLUSIONS: The TS correlates directly with risk of malignancy in this serie, with 92.9% of the testicular lesions smaller than 10 mm being compatible with benignity, which could raise CS in these patients. Source of Funding: None © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e1159-e1159 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Gema del Pozo Jiménez* More articles by this author Ignacio Castillón Vela More articles by this author Jorge Turo Antona More articles by this author Alfonso Gimeno Collado More articles by this author Joaquin Carballido Rodríguez More articles by this author Expand All Advertisement PDF downloadLoading ...
DOI: 10.1097/ju.0000000000000962.018
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: bronze
OpenAlex ID: W3022073505
FWCI:
Cites:
Cited by:
Related to: 10