Get started
Work

Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance

Year: 2020
Type: article
Abstract: Posttranslational modifications by phosphorylation can change protein activities, binding partners, or localization. Tyrosine 102 is conserved between delta papillomavirus BPV-1 and alpha papillomavirus HPV-31 E2. We characterized mutations of HPV-31 E2 for interactions with relevant cellular binding partners and replication in the context of the viral genome.
DOI: 10.1128/jvi.00590-20
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: green
Funders: McGill University, Virginia Commonwealth University, National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: The Indiana Cutaneous Biological Research Training Program, G2141828811, Control of Papillomavirus Expression and Transformation, G8222298131, G8883367568, G9000144900, G9000277884, Immunology and Infectious Diseases Training Program
OpenAlex ID: W3029894930
FWCI: 0.769
Cites: 50
Cited by: 8
Related to: 10