Year: 2020
Type: article
Study design: Case Report
Abstract: Filamentous basidiomycetes are uncommon agents of human diseases, despite their ubiquitous presence in the environment. We present a case of symptomatic pulmonary infection in a 38-year-old male with cough and fever; a thin-walled cyst in the posterior left upper pulmonary lobe was revealed by radiography. A non-sporulating fungus was isolated from sputum and biopsy material from the cyst. ITS and LSU sequences placed the fungus phylogenetically in Agaricales, family Cyphellaceae, and identified it as a member of shelf fungi in Gloeostereum, but without identity to any known species. The new species is described as Gloeostereum cimri. The clinical strain showed high MIC to voriconazole (>8 µg/ml) but had low MIC to amphotericin B (0.5 µg/ml).
Source: Emerging Microbes & Infections
Institutions: University of Khartoum, Westerdijk Fungal Biodiversity Institute, Radboud University Medical Center, Canisius-Wilhelmina Ziekenhuis, Santa Clara Valley Medical Center, CAB International, Thermo Fisher Scientific (Netherlands), Thermo Fisher Scientific (United States), California Institute for Medical Research, Stanford Medicine, Stanford University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,643
OpenAlex ID: W3029970693