Work

A metabolic pathway for bile acid dehydroxylation by the gut microbiome

Year: 2020

Type: article

Source: Nature

DOI: 10.1038/s41586-020-2396-4

Authors: Masanori Funabashi, Tyler L. Grove, Min Wang, Yug Varma, Molly E. McFadden, Laura C. Brown, Chunjun Guo, Steven Higginbottom, Steven C. Almo, Michael A. Fischbach

Institutions: Daiichi Sankyo RD Novare (Japan), Stanford University, Albert Einstein College of Medicine, Indiana University Bloomington, Indiana University, Stanford Medicine, Chan Zuckerberg Biohub San Francisco

Language: English

Topic: Steroid Chemistry and Biochemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, Price Family Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1303870094, G1338429717, G3034490871, The NYSGRC: A Large Scale Center for PSI:Biology, An integrative and generalizable approach to modulate microbiota small molecules in the host, Gut Microbiota and Cardiometabolic Diseases, G597898291, G7306070403, G87592374, G9000035971, G9000042503, G9000047645, G9000095292, G9000238359, G9000249039, G9000324075, G971691746

OpenAlex ID: W3036012425

FWCI: 16.1

Cites: 46

Cited by: 586

Related to: 10