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Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens

Year: 2020
Type: article
Abstract: Five new cassane-type diterpenoid heterosides, i. e. two cassane-type amides (1-2), two erythrophlamine-type amine esters (3-4) and a non‑nitrogenous erythrophlamine analogue (5) were isolated from the root barks (1-2) and the seeds (3-5) of Erythrophleum suaveolens. Their structures were unambiguously established by interpretation of their HRESIMS, 1D and 2D NMR data, and chemical degradation for sugar determination. Compounds 3-5 were evaluated for their cytotoxicity against a panel of three cell lines, revealing modest to strong activities.
Source: Fitoterapia
DOI: 10.1016/j.fitote.2020.104700
Authors: Ahmont Claude Landry Kablan, Jacques Dibi Konan, Gustav Komlaga, Faustin Aka Kabran, Ballo Daouda, Amon Diane N'Tamon, Tapé Kouamé, Adrien Jagora, Karine Leblanc, Blandine Seon-Méniel, Mehdi A. Beniddir, Koffi Barthélemy Attioua, Pierre Le Pogam, Pierre Champy
Institutions: Centre National de la Recherche Scientifique, Université Paris-Saclay, Université Pelefero Gon Coulibaly, Biomolécules : Conception, Isolement, Synthèse, Université Félix Houphouët-Boigny, Kwame Nkrumah University of Science and Technology
Language: English
Open Access status: hybrid
Estimated APC paid: $2,000
OpenAlex ID: W3047465645
FWCI: 0.276
Cites: 41
Cited by: 8
Related to: 10