Distribution, side involvement, phenotype and associated anomalies of Korean patients with craniofacial clefts from single university hospitalbased data obtained during 1998–2018
Year: 2020
Type: article
Study design: Observational Study
Abstract: Distribution, side involvement, phenotype and associated anomalies of Korean patients with craniofacial clefts from single university hospitalbased data obtained during 1998-2018 Objective: To investigate the distribution, side involvement, phenotype, and associated anomalies of Korean patients with craniofacial clefts (CFC).Methods: The samples consisted of 38 CFC patients, who were treated at Seoul National University Dental Hospital during 1998-2018.The Tessier cleft type, sex, side involvement, phenotype, and associated anomalies were investigated using nonparametric statistical analysis.Results: The three most common types were #7 cleft, followed by #0 cleft and #14 cleft.There was no difference between the frequency of male and female.Patients with #0 cleft exhibited nasal deformity, bony defect, and missing teeth in the premaxilla, midline cleft lip, and eye problems.A patient with #3 cleft (unilateral type) exhibited bilateral cleft lip and alveolus.All patients with #4 cleft were the bilateral type, including a combination of #3 and #4 clefts, and had multiple missing teeth.A patient with #5 cleft (unilateral type) had a posterior openbite.In patients with #7 cleft, the unilateral type was more prevalent than the bilateral type (87.0% vs. 13.0%,p < 0.001).Sixteen patients showed hemifacial microsomia (HFM), Goldenhar syndrome, and unilateral cleft lip and palate (UCLP).There was a significant match in the side involvement of #7 cleft and HFM (87.5%, p < 0.01).Patients with #14 cleft had plagiocephaly, UCLP, or hyperterorbitism.A patient with #30 cleft exhibited tongue tie and missing tooth.Conclusions: Due to the diverse associated craniofacial anomalies in patients with CFC, a multidisciplinary approach involving a well-experienced cooperative team is mandatory for these patients.
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W3095116166