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Askin tumor with clivus metastasis: an uncommon location

Year: 2021
Type: article
Abstract: localización infrecuente Dear Editor:Askin tumour is a rare and highly malignant neoplasm.1,2 Clivus metastasis is infrequent in these patients. To our knowledge, this is the first reported case of Askin tumour with clivus metastasis.Our patient is a 21-year-old man with no relevant medical history, who visited the ophthalmology department due to 7-month history of diplopia, without decreased visual acuity or eye pain. The neurological examination revealed oculomotor palsy of the ipsilateral third, fourth, and sixth cranial nerves, associated with impairment of sensory branches V1 Figure 1 A) Axial T1-weighted brain MRI scan showing a tumour in the clivus.B) 18 F-FDG PET study revealing a hypermetabolic mass in the right lung, with nodules in the left lower lobe (stars) and diffuse bone metastases (arrows).C) Round cell tumour proliferation. The histological study revealed cells with ill-defined cytoplasm and hyperchromatic nuclei (although most cells were non-nucleated), and abnormal mitosis.D) The immunohistochemical study revealed positivity for anti-CD99 antibodies.
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
Estimated APC paid:
OpenAlex ID: W3096306707
FWCI:
Cites: 7
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Related to: 10